› 2008
Kathryn Brown
› 2007
No Awards
› 2006
Peng H Tan
Imperial College, London
Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression.
› 2005
Mahzuz Karim
Nuffield Dept of Surgery, Oxford
Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process
› 2004
Nicola Monk
Deptartment of Nephrology and Transplantation Guy’s Hospital, London.
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade
› 2003
Julian R Pratt
Deptartment of Nephrology and Transplantation Guy’s Hospital, London
Local synthesis of complement component C3 regulates acute renal transplant rejection
› 2002
Emma Lovegrove
Dept. Surgery, Cambride
Epitope mapping of indirect T cell response to allogenic class I MHC: sequences shared by donor and recipient MHC may prime T cells that provide help for alloantibody production
› 2001
Nick Jones
Nuffield Dept. Surgery, Oxford
CD40-CD40 ligand- independent activation of CD8 positive T cells can trigger allograft rejection
› 2000
Gavin Pettigrew
Dept. SurgeryCambridge
Indirect T cell allorecognition and allo-antibody mediated rejection of MHC class I disparate heart grafts
› 1999
Sheng Yun
Institute of Child Health, London
Suppression of anti-porcine T-cell immune responses by major histocompatibility complex class II transactivator constructs lacking the amino terminal domain
› 1998
Louise Collins & Lorna Shewring
Institute of Child Health, London
A non-viral vector system for efficient gene transfer to corneal endothelial cells via membrane integrins
› 1997
Wilson Wong
Nuffield Dept. Surgery, Oxford
Pre-transplant administration of a single donor class 1 major histocompatibility complex molecule is sufficient for the indefinite survival of fully allogeneic cardiac allografts
› 1996
David Saitovitch
Nuffield Dept. Surgery, Oxford
Recipient cells expressing single donor MHC locus products can substitute for donor-specific transfusion in the induction of transplantation tolerance when pre-treatment is combined with anti-Cd4 monoclonal antibody
› 1995
Christopher Page
Heart Sciences Centre, Harefield
Human endothelial stimulation of allogenic T cells via a CTLA-4 independent pathway